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Description
NMDARs are voltage-dependent ionotropic glutamate receptors [409] and glutamate is a major excitatory neurotransmitter of the CNS

Enzyme-linked immunosorbent assay (ELISA) For the in vivo cytokine experiment, the hippocampus, prefrontal cortex, and amygdala of mice were obtained at day 5 postsurgery, or at 3 h after scopolamine or vehicle treatment after the neurobehavioral tests
These factors contribute to mitochondrial dysfunction and cognitive impairment in affected individuals ( 5.3 Manifestations of neuropsychiatric system injury Ketamine abuse commonly manifests as dissociative symptoms, such as altered consciousness, detachment from the environment, and sensory loss ( 5.4 Auxiliary examination Neuroimaging studies have provided critical insights into ketamine-induced neurotoxicity

In many individuals, the damage starts years earlier, silently progressing until it becomes visible