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Vitamin B12 is essential for neurological health

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The applied ICA-1s concentration (23.4 mmol/l) was determined as the equivalent in-vitro concentration considering the highest tested in-vivo concentration (200 mg/kg) for an average volume of the blood of a mouse (1.0 ml) and an average weight of a mouse (30.0 g)

References suggest it as a tetrasubstituted variant of the shortest functional GHRH sequence, denoted GRF (1-29)
