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However, some bacteria are able to bypass the protective binding IF, as in the case of Gram-negative anaerobes of the genus Bacteroides [76]

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To complement the Jadad score, the Cochrane Risk of Bias Tool (RoB 2) (Sterne et al., 2019) was also used for RCTs to provide a domain-based qualitative evaluation, assessing risks related to selection, performance, detection, attrition, and reporting
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