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The hypothesis was spread as the Barker hypothesis or fetal programming hypothesis, which suggests that unfavorable environmental factors during early life (intrauterine and postnatal) lead to a high incidence of metabolic diseases, such as hypertension, impaired glucose tolerance, insulin resistance, and T2DM (5, 6)

This work was supported by the Natural Science Foundation of Gansu Province (grant number: 23JRRA1282), the Innovation and Entrepreneurship Fund for Outstanding Graduate Students of the Gansu Provincial Department of Education (grant number: 2026CXCY-356), and the Intramural Research Fund of Gansu Provincial People's Hospital (grant number: 24GSSYH-5)

International Journal of Clinical Pharmacology and Therapeutics, 43 (2), 7177

Final Thoughts Cartalax, BPC-157, and TB-500 represent three fundamentally different approaches to connective tissue biology