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In neuroblastoma cells, MEHP also increased the protein expression of the Notch signaling cascade, thereby inducing cell proliferation and inhibiting apoptosis [152]
doi: 10.1016/j.biopsych.2018.04.016
However, the associated expenses and post-surgical pain impose a huge burden on these patients
Such compounds are able to inhibit SystemX c , thus leading to exhaustion of cysteine in cells, GPX4 inactivation, accumulated lipid peroxides, and eventually ferroptotic cell death
