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Who should avoid this treatment

Participants Twenty-four healthy subjects (12 men, 12 women) with a mean SD age of 25.3 3.0 years (range: 2134 years) were recruited from the University of Basel

This discrepancy may arise in part because the majority of B12 in serum is bound to the transport protein haptocorrin which is not physiologically active and thus unavailable for B12-dependent enzymatic reactions in cells (Green et al., 2017)
