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Wang X, Yang F, Liu C, Zhou H, Wu G, Qiao S, Li D, Wang J (2012) Dietary supplementation with the probiotic Lactobacillus fermentum I5007 and the antibiotic aureomycin differentially affects the small intestinal proteomes of weanling piglets

UV light catalyzes copper ion oxidation, which breaks the peptide-copper coordination bond and renders the compound biologically inactive

[Abstract]2020 Sep 22;16(9):e1008952

Thus, the data from this study support the notion that BH4 can improve oxidative damage and methylation abnormalities in children with ASD with a large effect size, with the caveat that this effect may be more pronounced in those with the more severe abnormalities at baseline