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For example, in prostate cancer cells, it elevates the expression of the pro-apoptotic protein Par-4 and activates downstream caspases, while in cervical cancer cells, it reinstates p53 expression, thereby stimulating Bax and other pro-apoptotic members of the Bcl-2 family to induce cell death [109]

AOD-9604 was originally developed as a potential anti-obesity drug due to its ability to promote fat loss without significantly impacting muscle growth or insulin levels

While physical dependence is rare when used as prescribed, it is important to follow dosing guidelines and attend all follow-ups to ensure responsible use

It is advisable not to apply a large amount to avoid unwanted residue