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[PubMed] [Google Scholar] 20

2008;295:E10008

Quantification of chronic functional mitral regurgitation by automated 3-dimensional peak and integrated proximal isovelocity surface area and stroke volume techniques using real-time 3-dimensional volume color Doppler echocardiography: in vitro and clinical validation

In the skin, this can manifest as a dull complexion, pigmentation spots, or premature wrinkle formation
