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Clinical research confirms that 1000 mg NR doses twice daily can boost steady-state, whole-blood NAD+ levels up to 2.7-fold after one dose [4]
Mitigative Effects on DM Complications (Figure 1D) CGA reduces glomerular hypertrophy and proliferation and mesangial cell expansions, decreases kidney malondialdehyde (MDA) levels, increases antioxidants (such as SOD, CAT, and GSH-Px), and reduces factors associated with oxidation and inflammation (such as IL-6, TNF-, COX-2, and IL-1) in the kidney of a diabetic nephropathy rat model [127,128]
