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10.1186/1475-2867-12-11 Cancer Cell Int

For the rs4673 polymorphism, different rates of O 2 - production have been demonstrated depending on the genotype
Onset and progression in inherited ALS determined by motor neurons and microglia

Intracellularly, lactate metabolism via LDH-A (pyruvate to lactate) and LDH-B (lactate to pyruvate) further fuels this reprogramming
