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A two-stage design for a phase II clinical trial of coenzyme Q10 in ALS
271 Matrix protein R-spondin 2 inhibits activation of the canonical Wnt/-catenin pathway and lymphangiogenesis, and the resulting suppression of cholesterol efflux from atherosclerotic arteries, 277 suggesting a novel role of Wnt in arterial cholesterol efflux

Under mild oxidative stress the oxidation of thiol residues favors the recruitment of Hsp90 thereby protecting SENP3 from binding to CHIP, which results in its ubiquitination and subsequent elimination via proteasomal degradation
