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Recently, increased IGF-I expression was reported in obese children with non-alcoholic fatty liver disease (NAFLD) and it was combined with upregulation of IGF1R (96), not expressed in the normal liver but involved in liver repair, such as after liver resection in a mouse model (97)

American Journal of Clinical Nutrition, 115(4), 787-789
Many notice shifts in energy or appetite signals before the scale moves much
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