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Targeting Unc51-like Autophagy Activating Kinase 1 (ULK1) overcomes adaptive drug resistance in acute myelogenous leukemia

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10.3389/fendo.2022.989305 27 ChenY.ZouH.LuH.XiangH.ChenS

We have shown that the mtDNA-induced cGAS activation in the striatum leads to a robust type I interferon response, exacerbating neuroinflammation and accelerating neurodegeneration
