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Upregulation of EAAC1 may be a potential strategy in neurodegenerative diseases

10.1016/j.cbpb.2021.110706 29 HofsteeP.BarthoL.McKeatingD.HollandO.VanderlelieJ.CuffeJ.et al (2017)
To test this, we used sulfur(VI) fluoride exchange (SuFEx)-based click chemistry transformations, in which an iminosulfur oxydifluoride group reacts with primary and secondary aliphatic amines to completion in DMSOPBS mixtures, forming sulfamides or sulfuramidimidoyl fluorides (Fig
The results indicated a significant improvement in H-Y grading within the experimental group compared to the control group (MD = 0.15, 95% CI [0.28, 0.01], p = 0.03), with no observed heterogeneity ( I 2 = 0%, p = 1.00) (Figure 15)
