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Topical drug delivery relies on passive diffusion, and prolonged drug retention helps improve efficacy

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GST P1-1 binding properties have also been linked to the regulation of intracellular processes, for example, binding to tumor necrosis factor receptor-associated factor 2 blocking apoptosis [13] and regulating mitogen-activated protein kinases through protein-protein interactions [10,1416]

88 Mucilage-rich herbs such as Ulmus rubra (Slippery elm), Althaea officinalis (Marshmallow root), and Plantago ovata also protect the mucosal lining by forming a viscous barrier that reduces irritation and inflammation