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Groups at higher risk of deficiency include older adults (due to reduced stomach acid production), people following vegan or strict vegetarian diets (as B12 is naturally found almost exclusively in animal products), individuals with pernicious anaemia or other malabsorption conditions, those taking certain medications such as metformin or proton pump inhibitors long-term, and people with significant nitrous oxide exposure (including recreational use), which can inactivate B12 in the body

Methylcobalamin form is the active form of vitamin B12 and does not require conversion in the body to be used

The possibility of vitamin B(12) deficiency in addition to other micronutrient deficiencies should be considered in obese children

Megaloblastic anemia occurs when folate or vitamin B12 deficiency impairs DNA synthesis in rapidly dividing cells