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As research continues to advance, the combination of ferroptosis with existing therapies, such as chemotherapy, immunotherapy and targeted treatments, holds great potential for improving the prognosis and survival rates of PDAC patients

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Anti-human lung cancer activities and survey of glutathione reductase and glutathione S transferase inhibition properties with molecular modeling studies of 2-hydroxy-5-methyl-3-nitroacetophenone: a pre-clinical trial study More details Hide details 1 Department of Thoracic Surgery, Shaanxi Province Peoples Hospital, Xi an city, China 2 Department of Cardiovascular Surgery, Xijing Hospital, The Fourth Military Medical University, Xian, China 3 Biology Department, College of Science, King Khalid University, Abha, Saudi Arabia 4 Zoology Department, College of Science, Damanhour University, Damanhour, Egypt 5 Pathology Department, College of Medicine, Taif University, Taif, Saudi Arabia Submission date: 2021-04-15 Final revision date: 2021-05-01 Acceptance date: 2021-05-03 Online publication date: 2021-05-14 Corresponding author Yawei Dou Shaanxi Province People's Hospital, China Introduction: The molecular docking method was found to calculate the biological activity of the 2-hydroxy-5-methyl-3-nitroacetophenone (2-H-5- M-3-N) molecule against the enzymes studied