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Healthcare providers often rely on a persons report of the uncomfortable effects of constipation such as bloating, excessive gas, straining and even pain due to hard, dry stools as the best indicator that he or she is experiencing constipation

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Accurate recognition of the cutaneous manifestations and eventual systemic involvement is essential in establishing a diagnosis

Brain-derived neurotrophic factor released from blood platelets prevents dendritic atrophy of lesioned adult central nervous system neurons
