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This is achieved by activating the UPR signaling and promoting the recruitment of messenger RNA to ER membranes for translation

In cancer research there has been a resurgence of interest in targeting metabolic mediators of the Warburg effect, whereby cancer cells upregulate anaerobic glycolysis even in the presence of sufficient oxygen

[DOI] [PMC free article] [PubMed] [Google Scholar] 156.Marshall S.A., Qin C.X., Jelinic M., OSullivan K., Deo M., Walsh J., Li M., Parry L.J., Ritchie R.H., Leo C.H

In a recent large-scale Mendelian randomized analysis, based on the European population cancer GWAS, the authors found that circulating vitamin E was significantly associated with an increased risk of bladder cancer (Xin et al., 2022)