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The intestines and liver are anatomically and functionally interconnected, forming the so-called gut liver axis [101,102,103,104,105]

A 2025 systematic review identified 36 studies from 1993 to 2024, including 35 preclinical studies and only 1 clinical study

In addition, the severity of nephrosclerosis was associated with the extent of leukocyte accumulation (93)

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