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Herbal medicinal therapies (e.g., AC591, Acorus calamus , Camellia sinensi , Cannabis species, Curcuma longa , Ginkgo biloba , and Matricaria chamomilla ) counteract the phenomena underlying CIPN, i.e., they attenuate inflammation and reduce oxidative stress in animals [206, 207]

Bisulfite sequencing, which involves DNA denaturation and treatment with sodium bisulfite, has long been regarded as the gold standard for DNA methylation sequencing and is still widely used

Valko M, Izakovic M, Mazur M (2004) Role of oxygen radicals in DNA damage and cancer incidence

The supernatant was then removed, and cells grown in MEM + 2% NCS containing carboxy-methylcellulose for 4 days