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Description
Reduced glutathione, commonly known as glutathione or GSH, is a tripeptide consisting of L-glutamine, L-cysteine, and glycine
Although WT -GCS-GS is nearly uninhibited by GSH (Ki 140 mM), shorter -GCS domain constructs were unexpectedly found to be strongly inhibited (Ki 15 mM), reproducing a physiologically important regulation seen in monofunctional -GCS enzymes
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