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doi: 10.1016/j.joms.2009.09.045

Future studies should include both sexes to enhance translational relevance

Some common impact may include eye disease like nigh blindness, dry eyes, permanent blindness

Further, biomarker concentrations are tricky to interpret: Total GSH concentration often fails to accurately reflect redox balance, which is better indicated by the GSH to GSSG ratio, plasma/serum concentrations are often a weak correlate of tissue level (the locus of action), and compartmentalization within cells (cytosol versus mitochondria) adds another layer of complexity often out of grasp in clinical samples [31]