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Dysregulated endosomal trafficking contributes to type I interferon activation via signalling through Toll-like receptors, aberrant autoantigen presentation, and altered expression of metabolite transporters in immune cells and target organs
The solution should have no sediment, layering, or turbidity
Work to minimize environmental and lifestyle contributors
Transgenic methods have also evolved considerably [663,670,671,672], and newer technologies such as CRISPR-Cas9 are believed to be effective in improving these processes [673,674,675,676]
