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The granularity of the model determines how many equations are needed, with coarse grained models of protein transcription, translation, and degradation having as few as four equations 353,354 and complex models of reaction networks 351,355 requiring hundreds of equations

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10.1016/j.ijpharm.2024.124962 24 FanK.JiaX.ZhouM.WangK.CondeJ.HeJ.et al (2018)