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From a biomechanical point of view, disc regeneration may only occur under conditions of restoration of pressure and load distribution within the disc

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Inhibition of major histocompatibility complex II expression and antigen processing in murine alveolar macrophages by Mycobacterium bovis BCG and the 19-kilodalton mycobacterial lipoprotein

There are some mechanisms relating to ganglion cell death during macular degeneration, including high intraocular pressure (IOP) and hypoxia, oxidative or nitrative stress, glutamate toxicity, loss of neurotrophic factors, and autoimmune reactions assisting in the degeneration of retinal ganglion cells