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For instance: Genetic causes include chromosomal and inherited conditions (e.g., errors in genetic code or epigenetic code) Developmental and environmental factors include prenatal exposure to infections and toxins Environmental or acquired factors include prenatal trauma (e.g., prematurity) Sociocultural actors Deprivation of nutrition, nurturance and social stimulation

Oxidative inflammatory injury may occur through the inhibition of SIRT1 and BDNFTrkB

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Recent reviews have examined the therapeutic relevance of NSCs in neurodegeneration, highlighting both preclinical advances and clinical trials (Lutfi Ismaeel et al., 2023)