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Description
Chronological (Intrinsic) Aging Intrinsic or chronological aging is a natural process with the passage of time that causes inflammation with the production of reactive oxygen species (ROS) resulting in oxidative stress from cellular metabolism, which results in a loss of skin homeostasis [9, 10, 14] (Fig
Dull or dehydrated skin that lacks glow : When the skin barrier is weak or congested, brightness naturally declines
Why do some make it and others not
To develop more efficacious treatments, an intricate understanding of the underlying pathophysiological mechanisms remains paramount
