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Glutathione is a water-soluble active that does not readily penetrate the skin on its own, which is why advanced formulation strategies are essential to enhance its delivery and bioavailability

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The MINERVA project exemplifies this interdisciplinary vision by aiming to integrate five functionally distinct compartments: microbiota, gut epithelium, immune cells, BBB, and brain, into a connected platform, thereby enabling the stepwise exposure of neuronal tissue to microbe-derived products under near-physiological conditions (201)