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46 LncExACT1 also positively regulates its closest protein-coding gene DCHS2 and reduced lncExACT1 activates YAP, which mediates the effect of lncExACT1 on cardiomyocyte growth and proliferation
It also impairs base and nucleotide excision repair pathways and causes widespread epigenetic dysregulation, such as aberrant DNA methylation and histone modification, that silence tumor suppressor genes [176]
Mustaqeem and A
