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The interaction between PINK1/Parkin and PGC-1 appears to co-regulate mitochondrial biogenesis and mitophagy, thereby maintaining mitochondrial homeostasis and mitochondrial quality control

doi:10.3389/fnut.2019.00093

Additional Benefits of B12 for Mood People who experience seasonal mood changes or those under prolonged stress often find relief from mood swings when supplementing with B12
