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Nat Rev Rheumatol

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Excessive iron ions can activate the p38-MAPK pathway and block the PI3K/AKT and JAK/STAT3 signaling pathways, thereby inducing death in MC3T3-E1 cells [149]

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However, the immune response of the CNS is complex and involves a myriad of diverse cell populations such as astrocytes, microglia, macrophages, NK cells, and T and B cells (Dringen and Arend, 2025)

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L.HeratL

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