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Cortisol can affect brain function by binding to glucocorticoid receptors (GR) in the hippocampus, amygdala, and prefrontal cortex of the brain (Carabotti et al., 2015)

2013;85(2):74552 Levey AS, Bosch JP, Lewis JB, Greene T, Rogers N, Roth D
+- Vida 2018

The druglike and orally bioavailable compounds identified herein are active in animal models of schistosomiasis with a broader range of developmental stages targeted than the drug of choice, PZQ
