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25 In the absence of genetic testing, cascade testing of relatives of index cases may be carried out using measurement of fasting LDL-C, with age-and gender-specific levels (Figure 4)

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Although transcript levels of PPP ratelimiting enzyme glucose-6-phosphate 1-dehydrogenase (GSPD-1) as measured by qRT-PCR were expectedly increased (2.8-fold) in WT during HS (Stincone et al, 2015