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8,9 Pain modulation takes place via the descending pathway from the brain to the neurons in the dorsal horn of the spinal cord
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This may lead to impairment of cellular signaling mechanisms and accumulation of misfolded proteins causing proteotoxicity associated with cardiac dysfunction (136143)

It is noteworthy that, once catalyzed, lipid peroxidation induces a cascade of chain reactions until cessation derivatives are generated [104, 107, 108]
Multimodal spatial proteomic profiling in acute myeloid leukemia
