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[32] In 1812, the chemist Jean-Pierre-Joseph d'Arcet further experimented with the use of hydrochloric acid to extract gelatin from bones, and later with steam extraction, which was much more efficient

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Monitor factors that might affect absorption: oral pH, hydration level, time of day, position of drops under tongue

*Correspondence: Kamil Kua, [email protected];[email protected] Jaevi, [email protected] ORCID: Jelena Dumanovi, orcid.org/0000-0002-8078-9878 Eugenie Nepovimova, orcid.org/0000-0003-0281-246X Maja Nati, orcid.org/0000-0002-6610-297X Kamil Kua, orcid.org/0000-0001-9664-1109 Vesna Jaevi, orcid.org/0000-0001-5137-2638 These authors have contributed equally to this work This article was submitted to Plant Cell Biology, a section of the journal Frontiers in Plant Science Disclaimer All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers