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Research into the effect of curcumin on ovarian follicles observed that the width and numbers of primary, secondary, and tertiary follicles increased

Thus, it is evident that the liver is a significant target organ for EGCG toxicity

Despite this complexity, numerous studies have reached conclusions on the intricate process of ASM remodeling, which includes ASM cell proliferation and apoptosis (255, 256), dysregulation Ca2+ homeostasis (257259), excessive production of ECM components like fibronectin and collagen type I that play a role in stimulating the proliferation of human ASM cells (260264), and factors associated with immune cells, airway cells, growth factors, cytokine and inflammatory mediators (263, 265268)

This patient with a history of severe facial eczema is likely chronically applying a topical steroid, which led to her subsequent acneiform eruption