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Description
HIF-1 promotes the glycolytic switch in hypoxic macrophages, and ATP levels are greatly reduced in HIF-1-deficient macrophages 36

The next FDA review is July 23, 2026, so keep an eye out for updates

A family of transcription factors, sterol-regulatory element-binding proteins, was first characterized in Schizosaccharomyces pombe , which mediates oxygen-dependent sterol synthesis and growth under hypoxic conditions (80)
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doi:10.1111/j.1365-2265.2006.02676.x
