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10.1016/j.febslet.2011.07.017 72 TakiguchiS.InoueK.MatsusueK.FurukawaM.TeramotoN.IguchiH

This study analyzed the therapy effects and adverse reactions of the two groups and found that contrasted with the control group, the whole effective percentage of remedy was 82.22% (37/45), the whole effective percentage of the observation group was 95.56% (43/45), has a significant increase ( P 0.05)

Why This Matters in MCAS Many MCAS patients present with: Abdominal pain with hypersensitivity quality Post-prandial flares IBS-like patterns Burning GI discomfort without structural pathology Persistent symptoms despite antihistamines and mast cell stabilizers In these scenarios, symptoms may reflect mast cellnerve cross-talk rather than uncontrolled mediator release alone

MOTS-c is of special interest in research exploring exercise mimetic effects, fat metabolism, and metabolic syndrome models