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5 Conclusions Our study has enabled a PK/PD model to be constructed that accurately describes and predicts the pharmacokinetics and IGF-I response of once-daily GH in both GHD adults and children, although it should be noted that the model is an experimental tool not approved by regulatory authorities

The HPLC/ECD but not DTNB and Oxiselect assays yielded quantitative GSH data but all three assays reflected nicely the qualitative redox changes and functional impairment in hypertensive rats

[DOI] [PMC free article] [PubMed] [Google Scholar] 87.Mettenleiter TC

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