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In the human monocytic cell line U937, IL-4 receptor engagement leads to ChoK-independent increases of phosphocholine, resulting from the degradation of membrane PC into DAG, indicating enhanced PC-specific phospholipase C activity (81)

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A fertility specialist may consider antioxidant or nutrient support in men who have: low or borderline motility on repeated semen analysis idiopathic infertility suspected oxidative stress lifestyle-related sperm issues varicocele after proper assessment fertility-treatment planning where sperm optimisation is being discussed That conversation usually works best alongside: repeat semen testing if needed history and examination hormone evaluation in selected men varicocele assessment where appropriate infection or inflammation work-up where relevant couple-based planning, not sperm-only thinking What to look for in a formulation Before choosing any male fertility supplement, ask: Questions to ask before choosing a supplement Does it contain ingredients that have actually been studied for motility or oxidative stress