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One level up: abnormal proteolytic regulation of IGF activity plays a role in human pathophysiology

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Vibegron demonstrates favorable safety and tolerability, with common adverse effects including headache, nasopharyngitis, and diarrhea

Mutat Res Lett 262:4146 Clementino M, Xie J, Yang P, Li Y, Lin HP, Fenske WK, Tao H, Kondo K, Yang C, Wang Z (2020) A positive feedback loop between c-Myc upregulation, glycolytic shift, and histone acetylation enhances cancer stem cell-like property and tumorigenicity of Cr(VI)-transformed cells
