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Description
An adenovirus carrying ferritin light chain/heavy chain and transferrin can up-regulate NF-B/INOS and down-regulate Nrf2/GPX4 in the ovaries of 3-month-old rats, confirming that oxidative stress-inflammatory response is mediated by iron homeostasis disorder in ovarian aging
These findings are preliminary and may not translate to effects in humans
overexpressed Grx2 in HeLa cells, which caused less sensitivity to doxorubicin and 2-deoxy-D-glucose (2-DG)
doi: 10.1136/annrheumdis-2018-214620 114 HuangAZhangBWangBZhangFFanK-XGuoY-J
