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In ischemic kidney injury, iron chelators such as deferoxamine, deferiprone, and lipophilic antioxidants have been shown to inhibit lipid peroxidation and protect against cell damage [423]

Compared with the placebo group, the experimental group (receiving 500 mg of daily magnesium supplementation) showed improvements in sleep efficiency, sleep duration, sleep onset latency, and early-morning awakening frequency.82 A study performed on rats revealed a strong correlation between forebrain magnesium concentration and sleep duration.39 A recent systematic review, encompassing 7582 participants from 9 published cross-sectional, cohort, and randomized controlled studies, also identified an association between magnesium status and sleep quality.83 The findings demonstrated that in healthy adults, higher magnesium intake was correlated with various sleep quality parameters, including daytime sleepiness, drowsiness, snoring, and sleep duration

In some cases, the neurological damage to the dorsal column of the spinal cord was severe enough to be detected on magnetic resonance imaging (Carroll et al., 2017

For R3, we removed either of the chloro groups from the dichlorobenzene to decrease the molecular weight of the compounds