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10.3389/fcvm.2021.811670 83 LiuF.WangC.GaoY.LiX.TianF.ZhangY.et al (2018a)

Lastly, the use of 100% female population may allow the results to be conclusive among female models only

The estimated net effect sizes were medium (defined as Cohens d of 0.50.79) for the Average of all scores, Overall, tantrums/meltdowns, cognition/thinking, and receptive language, and small (defined as 0.20.49) for play/leisure skills, sleep, eye contact, stools/GI problems, expressive language/speech, and sociability)

Addressing hormonal imbalances can support more effective weight loss for eligible patients