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Description
The reads were aligned to the mouse genome (mm10) using bcbio-nextgen (v1.2.9), which includes Bowtie2 (v2.2.5) 18 , Samtools (v1.13) 19 , and Sambamba (v0.8.2) 20,21
Differential signalling potential of insulin and IGF-1 receptor cytoplasmic domains
JAMA Oncology 11(11):1400, 2025
Hence, we chose only a single concentration of QCT (2 mg/kg) based on a prior study 44 , a relatively low dose compared to the commonly used range of 10100 mg/kg 45,46 , for our in vivo experiments
