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Description
GPx4 shares the amino acid motif of selenocysteine, glutamine, and tryptophan (catalytic triad) with other GPxs

This observation suggested that GPX4 depletion may predispose tumor cells to ferroptosis

MilkovicLCipak GasparovicACindricMMouthuyPAZarkovicN

AMB Express 2019, 9 (1), 175