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Description
Before the approval of PT-141, there were limited treatment options for HSDD

Degranulation products, such as histamine, cytokines, chemokines, proteases, and nitric-oxide, have further immune and defensive roles

BPC 157, also known as PLD-116, PL-10, PL14736 [9], or Bepectin [10,11,12,13,14,15,16,17], has recently attracted considerable attention as a potential drug candidate that is stable in acidic environments and has no serious adverse effects [18], although it has been known to cause pain and/or necrosis when injected in an aqueous solution or in physiological saline [19]

Consequently, the lesions induced in rats share a considerably high degree of similarity with corresponding lesions in human patients
