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Description
In STEP 1, roughly 86% of semaglutide participants lost at least 5% body weight, 69% lost at least 10%, and 50% lost at least 15%

Evidence for the involvement of calcitonin gene-related peptide in the epithelium-dependent contraction of Guinea-pig trachea in response to capsaicin
But individual response varies enormously

The study was registered with the ClinicalTrials.gov database (NCT04392011) and was conducted at the WSU Clinical Research Unit on the Health Sciences Campus under Investigational New Drug status (#145002) and in accordance with the Code of Federal Regulations on the Protection of Human Subjects (45 CFR Part 46)
